Feel like yourself again SPRAVATO®, the only FDA-approved nasal spray for adults with treatment-resistant depression, reduces depression symptoms when two or more oral antidepressants haven’t worked. SPRAVATO® can be taken with or without an oral antidepressant.

SPRAVATO® works differently by acting on glutamate • Glutamate is a chemical messenger found in the brain that is thought to help balance well-being and depression